Pharmacy Pharmacology 3

Question 1

What is the mechanism of action of ACE inhibitors in treating hypertension?

Accepted Answer

Inhibit the conversion of angiotensin I to angiotensin II

Answer

Block calcium channels in vascular smooth muscle

Answer

Block aldosterone receptors in the kidney

Answer

Stimulate beta-2 receptors causing vasodilation

Question 2

SSRIs are first-line treatment for depression because they selectively inhibit reuptake of which neurotransmitter?

Accepted Answer

Serotonin

Answer

Dopamine

Answer

Norepinephrine

Answer

GABA

Question 3

Warfarin inhibits which vitamin to exert its anticoagulant effect?

Accepted Answer

Vitamin K

Answer

Vitamin A

Answer

Vitamin C

Answer

Vitamin D

Question 4

Which opioid receptor is primarily responsible for analgesia and euphoria?

Accepted Answer

Mu (μ)

Answer

Delta (δ)

Answer

Kappa (κ)

Answer

Sigma (σ)

Question 5

A patient taking a monoamine oxidase inhibitor (MAOI) should avoid which food to prevent hypertensive crisis?

Accepted Answer

Aged cheeses

Answer

Grapefruit

Answer

Leafy green vegetables

Answer

Dairy products

Question 6

The first-pass effect refers to a drug being significantly metabolized in the:

Accepted Answer

Liver before reaching systemic circulation

Answer

Kidneys before reaching systemic circulation

Answer

Lungs before reaching systemic circulation

Answer

Small intestine before being absorbed