Pharmacology Drug Classifications and Prototypes 2 — Questions and Answers
Question 1: Which drug is considered the prototype beta-1 selective adrenergic blocker?
- Propranolol
- Metoprolol (Correct answer)
- Atenolol
- Labetalol
Correct answer: Metoprolol
Metoprolol is the prototype cardioselective (beta-1 selective) beta-blocker, widely used for hypertension and heart failure.
Question 2: Hydrochlorothiazide is the prototype of which diuretic class?
- Loop diuretics
- Potassium-sparing diuretics
- Thiazide diuretics (Correct answer)
- Osmotic diuretics
Correct answer: Thiazide diuretics
Hydrochlorothiazide is the prototype thiazide diuretic, acting on the distal convoluted tubule to inhibit sodium reabsorption.
Question 3: Which drug is the prototype first-generation H1 antihistamine?
- Loratadine
- Cetirizine
- Diphenhydramine (Correct answer)
- Fexofenadine
Correct answer: Diphenhydramine
Diphenhydramine (Benadryl) is the prototype first-generation H1 antihistamine, known for causing significant sedation due to CNS penetration.
Question 4: Morphine serves as the prototype for which drug class?
- NSAIDs
- Opioid analgesics (Correct answer)
- Tricyclic antidepressants
- Benzodiazepines
Correct answer: Opioid analgesics
Morphine is the prototype opioid analgesic, acting on mu-opioid receptors to produce analgesia, sedation, and euphoria.
Question 5: Which drug is the prototype calcium channel blocker of the dihydropyridine class?
- Verapamil
- Diltiazem
- Nifedipine (Correct answer)
- Amlodipine
Correct answer: Nifedipine
Nifedipine is the prototype dihydropyridine CCB, acting primarily on vascular smooth muscle with little effect on cardiac conduction.
Question 6: Chlorpromazine is the prototype for which drug classification?
- Atypical antipsychotics
- Typical (first-generation) antipsychotics (Correct answer)
- Mood stabilizers
- Tricyclic antidepressants
Correct answer: Typical (first-generation) antipsychotics
Chlorpromazine is the prototype first-generation (typical) antipsychotic, primarily acting as a D2 receptor antagonist.
Question 7: Which drug class does warfarin belong to as its prototype anticoagulant?
- Direct thrombin inhibitors
- Factor Xa inhibitors
- Vitamin K antagonists (Correct answer)
- Heparin derivatives
Correct answer: Vitamin K antagonists
Warfarin is the prototype vitamin K antagonist anticoagulant, inhibiting synthesis of clotting factors II, VII, IX, and X.
Pharmacology Drug Classifications and Prototypes 2
Which drug is considered the prototype beta-1 selective adrenergic blocker?