Pharmacology Autonomic Nervous System Pharmacology 2

Question 1

A patient with pheochromocytoma requires surgical removal. Which alpha-blocker is used preoperatively to prevent hypertensive crisis?

Accepted Answer

Phenoxybenzamine

Answer

Prazosin

Answer

Tamsulosin

Answer

Doxazosin

Question 2

Which muscarinic receptor subtype is primarily responsible for the decrease in heart rate caused by vagal stimulation?

Accepted Answer

M2

Answer

M1

Answer

M3

Answer

M4

Question 3

Bethanechol is used to treat postoperative urinary retention. What is its mechanism of action?

Accepted Answer

Directly stimulates muscarinic receptors

Answer

Blocks muscarinic receptors

Answer

Activates nicotinic receptors

Answer

Inhibits acetylcholinesterase

Question 4

A patient takes a non-selective beta-blocker and later uses an epinephrine auto-injector. Which cardiovascular effect is most likely?

Accepted Answer

Severe hypertension with bradycardia

Answer

Hypotension with reflex tachycardia

Answer

Hypotension with bradycardia

Answer

Tachycardia with vasodilation

Question 5

Which drug causes mydriasis and cycloplegia by blocking muscarinic receptors in the eye?

Accepted Answer

Atropine

Answer

Pilocarpine

Answer

Physostigmine

Answer

Neostigmine

Question 6

Guanethidine lowers blood pressure by which mechanism?

Accepted Answer

Depleting norepinephrine from sympathetic nerve terminals

Answer

Blocking alpha-1 receptors

Answer

Stimulating central alpha-2 receptors

Answer

Inhibiting MAO

Question 7

Which beta-2 agonist is used as a tocolytic to suppress premature uterine contractions?

Accepted Answer

Ritodrine

Answer

Metoprolol

Answer

Dobutamine

Answer

Carvedilol