PANRE PANRE 4

Question 1

A 68-year-old man on aspirin and clopidogrel after a coronary stent presents with melena. Vitals are stable. Which is the most important next step?

Accepted Answer

Administer IV proton pump inhibitor and consult cardiology before stopping antiplatelets

Answer

In patients with recent stents, abruptly stopping antiplatelets risks stent thrombosis; IV PPI and cardiology consultation are needed before altering antiplatelet therapy.

Question 2

A newborn develops jaundice within the first 24 hours of life. Mother is blood type O negative, baby is A positive. Which condition is most likely?

Accepted Answer

ABO hemolytic disease of the newborn

Answer

Jaundice appearing within 24 hours is pathologic; ABO incompatibility with O-negative mother and A-positive infant causes hemolytic disease of the newborn.

Question 3

A 60-year-old woman with a history of breast cancer presents with hypercalcemia, constipation, polyuria, and confusion. Calcium is 13.5 mg/dL. What is the first treatment?

Accepted Answer

IV normal saline hydration

Answer

IV normal saline is the first-line treatment for hypercalcemia to restore volume depletion and promote renal calcium excretion.

Question 4

A 35-year-old man presents with bilateral knee pain, oral ulcers, and conjunctivitis after a recent episode of urethritis. Which is the most likely diagnosis?

Accepted Answer

Reactive arthritis

Answer

Reactive arthritis (formerly Reiter syndrome) is characterized by the classic triad of arthritis, urethritis, and conjunctivitis following a genitourinary or GI infection.

Question 5

A 52-year-old smoker presents with hemoptysis, weight loss, and a right hilar mass on chest X-ray. Biopsy shows small, dark cells with scant cytoplasm. Which treatment is most appropriate?

Accepted Answer

Chemotherapy and radiation

Answer

Small cell lung cancer is exquisitely sensitive to chemotherapy and radiation, making chemoradiation the primary treatment even in limited-stage disease.

PANRE Test Practice Test

PANRE Test Practice Test

PANRE PANRE 4