A 55-year-old smoker presents with progressive dyspnea and a barrel chest. Spirometry shows FEV1/FVC ratio of 0.60. Which pathophysiologic mechanism best explains his air trapping?
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A
Loss of elastic recoil causing dynamic airway collapse
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B
Bronchial smooth muscle hypertrophy
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C
Mucus gland hyperplasia obstructing large airways
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D
Alveolar wall thickening reducing diffusion capacity