PANCE Analysis Flashcards
7 cards from real PANCE practice questions. Tap to flip, then mark Knew It or Still Learning — missed cards come back until you master them.
Read the first 7 PANCE Analysis flashcards as text
A 40-year-old woman with rheumatoid arthritis presents with fatigue, pallor, and a hemoglobin of 9.5 g/dL. Iron studies show low serum iron, low TIBC, and elevated ferritin. What is the most likely cause of her anemia?
Answer: Anemia of chronic disease
Anemia of chronic disease shows low serum iron and TIBC with elevated ferritin, reflecting sequestration of iron by inflammatory cytokines.
A 62-year-old man presents with progressive dysphagia to solids more than liquids and a 20-lb weight loss over 3 months. He has a 40-pack-year smoking history. What is the most likely diagnosis?
Answer: Esophageal carcinoma
Progressive dysphagia to solids worse than liquids with significant weight loss in an older smoker is classic for esophageal carcinoma.
A neonate born at 28 weeks gestation develops respiratory distress within 2 hours of birth. CXR shows bilateral ground-glass opacities and air bronchograms. What is the underlying pathophysiology?
Answer: Surfactant deficiency
Respiratory distress syndrome in premature infants results from surfactant deficiency, leading to alveolar collapse and the characteristic ground-glass appearance.
A 55-year-old man with a history of alcohol use disorder presents with painless jaundice, clay-colored stools, and dark urine. Ultrasound shows dilation of the common bile duct. What is the most likely cause?
Answer: Pancreatic head carcinoma
Painless obstructive jaundice with dilated CBD in an older patient is the classic presentation of pancreatic head carcinoma compressing the bile duct.
A 30-year-old woman presents with a butterfly rash, joint pain, oral ulcers, and a positive ANA with anti-dsDNA antibodies. Which complication is most likely to determine her long-term prognosis?
Answer: Lupus nephritis
Lupus nephritis is the most serious complication of SLE and the leading cause of morbidity and mortality, requiring close monitoring of renal function.
A 19-year-old male athlete collapses during a basketball game. He is resuscitated from ventricular fibrillation. ECG shows ST elevation in V1-V2 with a right bundle branch block pattern. What is the most likely diagnosis?
Answer: Brugada syndrome
Brugada syndrome presents with the characteristic coved-type ST elevation in V1-V2 with RBBB pattern and is a cause of sudden cardiac death in young individuals.
A 68-year-old woman presents with polyuria, polydipsia, constipation, and confusion. Labs show calcium of 13.8 mg/dL and PTH is elevated. What is the most common cause of this presentation?
Answer: Primary hyperparathyroidism
Primary hyperparathyroidism is the most common cause of asymptomatic and symptomatic hypercalcemia with elevated PTH, typically due to a parathyroid adenoma.