PTCB Drug Test #6 3

Question 1

How many milliliters of a 20 mg/mL morphine injection are needed to provide a 15 mg dose?

Accepted Answer

0.75 mL

Answer

Volume = dose ÷ concentration = 15 mg ÷ 20 mg/mL = 0.75 mL.

Question 2

What is the generic name for Xarelto?

Accepted Answer

Rivaroxaban

Answer

Xarelto is the brand name for rivaroxaban, a direct Factor Xa inhibitor anticoagulant used for VTE prevention/treatment, pulmonary embolism, and stroke prevention in A-fib.

Question 3

Which of the following drug interactions is most clinically significant for simvastatin?

Accepted Answer

Concurrent use with strong CYP3A4 inhibitors (e.g., clarithromycin)

Answer

Simvastatin is metabolized by CYP3A4. Strong inhibitors like clarithromycin, ketoconazole, or HIV protease inhibitors dramatically increase simvastatin levels, raising the risk of myopathy and rhabdomyolysis.

Question 4

Which government form is used to order Schedule II controlled substances from a DEA-registered distributor?

Accepted Answer

DEA Form 222 (or CSOS)

Answer

DEA Form 222 (or its electronic equivalent CSOS - Controlled Substance Ordering System) is required to order Schedule I and II controlled substances from a registered distributor.

Question 5

Metoprolol tartrate 25 mg BID is equivalent to how many mg per day?

Accepted Answer

50 mg/day

Answer

BID = twice daily. 25 mg x 2 doses = 50 mg/day. Metoprolol tartrate is the immediate-release form (Lopressor) dosed multiple times daily, vs. metoprolol succinate (Toprol XL) which is once daily.

Pharmacy Practice Test

Pharmacy Practice Test

PTCB Drug Test #6 3