MFDS Human Disease 3

Question 1

Hyperthyroidism in a dental patient most relevantly affects dental management by:

Accepted Answer

Increasing sensitivity to adrenaline and potential for thyroid crisis

Answer

Hyperthyroid patients are very sensitive to catecholamines; adrenaline in LA solutions can precipitate hypertensive crisis or thyroid storm, necessitating cautious use.

Question 2

Osteogenesis imperfecta is associated with which oral condition?

Accepted Answer

Dentinogenesis imperfecta

Answer

Dentinogenesis imperfecta type I occurs in osteogenesis imperfecta due to defective type I collagen, producing opalescent discoloured teeth prone to attrition.

Question 3

Which condition is characterised by episodic severe hypertension, headache and sweating due to excess catecholamine secretion?

Accepted Answer

Phaeochromocytoma

Answer

Phaeochromocytoma is a catecholamine-secreting tumour of chromaffin cells of the adrenal medulla, causing episodic or sustained hypertension with severe headache, sweating and palpitations.

Question 4

Thrombocytopenia significant for dental practice (increased bleeding risk) is generally considered when platelets fall below:

Accepted Answer

50 × 10⁹/L

Answer

A platelet count below 50 × 10⁹/L is associated with significantly increased bleeding risk for invasive dental procedures; haematology consultation is advised below this threshold.

Question 5

Sickle cell anaemia patients face which specific risk during general anaesthesia?

Accepted Answer

Sickling crisis triggered by hypoxia, dehydration or hypothermia

Answer

Hypoxia, dehydration and hypothermia can trigger a sickling crisis in HbS patients; careful perioperative management is essential including optimal oxygenation and hydration.

MFDS Part 1 Practice Test

MFDS Part 1 Practice Test

MFDS Human Disease 3