CAS CAS Pharmacology & Medication-Assisted Treatment

Question 1

Methadone for opioid use disorder (OUD) must be dispensed through a federally certified:

Accepted Answer

Opioid Treatment Program (OTP)

Answer

Federal regulations require that methadone for OUD treatment be dispensed only through DEA-registered and SAMHSA-certified Opioid Treatment Programs.

Question 2

Buprenorphine is classified pharmacologically as a:

Accepted Answer

Partial opioid agonist

Answer

Buprenorphine is a partial opioid agonist, meaning it activates opioid receptors but produces a ceiling effect that limits respiratory depression and abuse potential compared to full agonists.

Question 3

Naloxone is combined with buprenorphine in Suboxone primarily to:

Accepted Answer

Deter intravenous misuse by precipitating withdrawal if injected

Answer

When Suboxone is taken sublingually as directed, naloxone has minimal effect, but if injected, naloxone precipitates immediate opioid withdrawal, deterring misuse.

Question 4

Naltrexone (Vivitrol) for OUD works by:

Accepted Answer

Blocking opioid receptors, preventing opioids from producing euphoria

Answer

Naltrexone is a full opioid antagonist that competitively blocks opioid receptors, so if opioids are used, they cannot produce euphoria or reinforcement.

Question 5

Which medication is FDA-approved for alcohol use disorder and works by causing an aversive reaction when alcohol is consumed?

Accepted Answer

Disulfiram

Answer

Disulfiram (Antabuse) inhibits aldehyde dehydrogenase, causing accumulation of acetaldehyde when alcohol is ingested, producing flushing, nausea, and palpitations as an aversive deterrent.

(CAS) Certified Addiction Specialist Practice Test

(CAS) Certified Addiction Specialist Practice Test

CAS CAS Pharmacology & Medication-Assisted Treatment