OEC Research Methods & Evidence-Based Practice 2 — Questions and Answers
Question 1: In evidence-based practice, what does the acronym PICO stand for?
- Patient, Intervention, Comparison, Outcome (Correct answer)
- Protocol, Indication, Contraindication, Observation
- Population, Injury, Care, Objective
- Procedure, Implementation, Criteria, Outcome
Correct answer: Patient, Intervention, Comparison, Outcome
PICO is a framework for forming clinical questions: Patient/Problem, Intervention, Comparison, and Outcome.
Question 2: Which level of evidence is generally considered the strongest in a hierarchy of evidence?
- Expert opinion and consensus statements
- Randomized controlled trials
- Case reports and case series
- Systematic reviews and meta-analyses (Correct answer)
Correct answer: Systematic reviews and meta-analyses
Systematic reviews and meta-analyses pool results from multiple high-quality studies, placing them at the top of most evidence hierarchies.
Question 3: An OEC technician reads that a new splinting technique 'showed statistically significant improvement (p = 0.03).' What does this mean?
- The technique improved outcomes by 3% in all patients
- There is a 3% chance the observed difference occurred by chance alone (Correct answer)
- The study enrolled only 3% of eligible participants
- The result was clinically meaningful in 97% of cases
Correct answer: There is a 3% chance the observed difference occurred by chance alone
A p-value of 0.03 means there is a 3% probability the results occurred by random chance under the null hypothesis.
Question 4: What is the primary purpose of a control group in a clinical study?
- To provide a comparison baseline against the experimental intervention (Correct answer)
- To receive the most effective known treatment available
- To increase the total sample size of the study
- To ensure participants are blinded to their group assignment
Correct answer: To provide a comparison baseline against the experimental intervention
A control group receives no intervention or a standard treatment, allowing researchers to compare outcomes against the experimental group.
Question 5: Which type of study design best establishes cause-and-effect relationships between an intervention and an outcome?
- Cross-sectional survey
- Retrospective cohort study
- Randomized controlled trial (Correct answer)
- Case-control study
Correct answer: Randomized controlled trial
Randomized controlled trials randomly assign participants to groups, minimizing confounding and best supporting causal inference.
Question 6: A wilderness first aid study reports a 95% confidence interval of 2–8 minutes for time to effective airway management. What does this interval indicate?
- All participants achieved airway management within 2–8 minutes
- Researchers are 95% confident the true population mean falls between 2 and 8 minutes (Correct answer)
- Only 95% of providers can complete the skill in under 8 minutes
- The study had a 5% error rate in timing measurements
Correct answer: Researchers are 95% confident the true population mean falls between 2 and 8 minutes
A 95% confidence interval means that if the study were repeated many times, 95% of such intervals would contain the true population parameter.
Question 7: When critically appraising a research article on OEC protocols, which question addresses internal validity?
- Can these results be generalized to all ski patrol settings?
- Was the study funded by an organization with a financial interest in the outcome?
- Were participants randomly assigned and were confounding variables controlled? (Correct answer)
- Does the journal have a high impact factor?
Correct answer: Were participants randomly assigned and were confounding variables controlled?
Internal validity concerns whether the study design correctly measured what it intended to, including randomization and control of confounders.
In evidence-based practice, what does the acronym PICO stand for?