NP NP Pharmacology & Prescribing 2

Question 1

A patient taking SSRIs is prescribed tramadol. Which serious drug interaction should the NP counsel the patient about?

Accepted Answer

Serotonin syndrome

Answer

Hypertensive crisis

Answer

Neuroleptic malignant syndrome

Answer

Stevens-Johnson syndrome

Question 2

Which medication requires baseline and periodic monitoring of serum creatinine and potassium when prescribed for heart failure?

Accepted Answer

Spironolactone

Answer

Carvedilol

Answer

Digoxin

Answer

Isosorbide mononitrate

Question 3

When prescribing fluoroquinolones, the NP should warn patients about which rare but serious adverse effect?

Accepted Answer

Tendon rupture

Answer

Agranulocytosis

Answer

Pulmonary fibrosis

Answer

Pseudotumor cerebri

Question 4

A patient with a penicillin allergy documented as 'hives and swelling' needs antibiotic coverage for a skin infection. The safest approach is to:

Accepted Answer

Use clindamycin or TMP-SMX as an alternative antibiotic class

Answer

Prescribe amoxicillin-clavulanate because cross-reactivity is rare

Answer

Administer penicillin under observation since allergies fade over time

Answer

Refer to allergy specialist before treating

Question 5

Which analgesic is contraindicated in elderly patients due to increased risk of GI bleeding, renal impairment, and falls per the Beers Criteria?

Accepted Answer

Indomethacin

Answer

Acetaminophen

Answer

Tramadol

Answer

Gabapentin

Question 6

An NP is prescribing thyroid hormone replacement. Which medication significantly impairs levothyroxine absorption if taken together?

Accepted Answer

Calcium carbonate antacids

Answer

Atorvastatin

Answer

Metoprolol

Answer

Sertraline