Neuropathy Inflammatory and Immune-Mediated Neuropathy

Question 1

What is the most common acute inflammatory demyelinating polyneuropathy?

Accepted Answer

Guillain-Barré Syndrome (GBS)

Answer

Chronic Inflammatory Demyelinating Polyneuropathy (CIDP)

Answer

Multifocal Motor Neuropathy

Answer

Vasculitic Neuropathy

Question 2

What duration of symptoms distinguishes CIDP from Guillain-Barré Syndrome?

Accepted Answer

Symptoms lasting more than 8 weeks

Answer

Symptoms lasting more than 2 weeks

Answer

Symptoms lasting more than 4 weeks

Answer

Symptoms lasting more than 6 months

Question 3

Which treatment is considered first-line for Guillain-Barré Syndrome?

Accepted Answer

Intravenous immunoglobulin (IVIG) or plasmapheresis

Answer

Oral corticosteroids alone

Answer

Broad-spectrum antibiotics

Answer

Nonsteroidal anti-inflammatory drugs (NSAIDs)

Question 4

What is the classic cerebrospinal fluid (CSF) finding in Guillain-Barré Syndrome?

Accepted Answer

Elevated protein with normal white blood cell count (albuminocytologic dissociation)

Answer

Elevated white blood cells with normal protein

Answer

Decreased glucose with elevated protein

Answer

Normal protein and normal white blood cell count

Question 5

Which antibody is strongly associated with Multifocal Motor Neuropathy (MMN)?

Accepted Answer

Anti-GM1 IgM antibodies

Answer

Anti-MAG IgM antibodies

Answer

Anti-Hu antibodies

Answer

Anti-GQ1b antibodies

Question 6

How does vasculitic neuropathy most typically present?

Accepted Answer

Asymmetric nerve involvement due to ischemia from vessel inflammation

Answer

Symmetric distal sensorimotor polyneuropathy

Answer

Pure sensory neuropathy affecting only small fibers

Answer

Proximal motor-dominant demyelinating neuropathy

Question 7

Approximately what percentage of GBS patients recover the ability to walk independently within 6 months?

Accepted Answer

About 85%

Answer

About 20-30%

Answer

About 50%

Answer

Nearly 100%