A 48-year-old client with co-occurring diagnoses of severe Alcohol Use Disorder and Post-Traumatic Stress Disorder (PTSD) is prescribed clonazepam (a benzodiazepine) by their primary care physician to manage anxiety and insomnia. The client reports to their counselor that the medication initially helped but now seems less effective at the prescribed dose. What is the MOST likely psychopharmacological reason for this phenomenon?
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A
The client has developed a paradoxical reaction to the medication.
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B
The medication is primarily metabolized by the liver, which is likely compromised.
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C
Cross-tolerance has developed between alcohol and the benzodiazepine.
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D
The client's PTSD symptoms are inherently resistant to anxiolytic medication.