NCCPA Pharmacology 3

Question 1

Which antiepileptic drug inhibits sodium channels AND is a first-line agent for trigeminal neuralgia?

Accepted Answer

Carbamazepine

Answer

Valproate

Answer

Levetiracetam

Answer

Phenobarbital

Question 2

A patient receiving aminoglycoside therapy should be monitored for which two major adverse effects?

Accepted Answer

Nephrotoxicity and ototoxicity

Answer

Hepatotoxicity and cardiotoxicity

Answer

Pulmonary toxicity and neurotoxicity

Answer

Myelosuppression and hepatotoxicity

Question 3

A patient with type 2 diabetes develops lactic acidosis while on metformin. Which condition most likely precipitated this complication?

Accepted Answer

Acute kidney injury

Answer

Hyperglycemia

Answer

Hyperlipidemia

Answer

Peripheral neuropathy

Question 4

Which anticoagulant's effect can be reversed by protamine sulfate?

Accepted Answer

Heparin

Answer

Warfarin

Answer

Rivaroxaban

Answer

Dabigatran

Question 5

Which immunosuppressant inhibits calcineurin, thereby blocking IL-2 transcription and T-cell activation?

Accepted Answer

Cyclosporine

Answer

Mycophenolate mofetil

Answer

Azathioprine

Answer

Sirolimus

Question 6

A patient on SSRIs is started on tramadol. What serious interaction should be anticipated?

Accepted Answer

Serotonin syndrome

Answer

QT prolongation

Answer

Hypertensive crisis

Answer

Agranulocytosis

Question 7

Which antihypertensive drug class is contraindicated in bilateral renal artery stenosis?

Accepted Answer

ACE inhibitors

Answer

Calcium channel blockers

Answer

Beta-blockers

Answer

Alpha-1 blockers