Internal Medicine Flashcards
7 cards from real NCCPA practice questions. Tap to flip, then mark Knew It or Still Learning — missed cards come back until you master them.
Read the first 7 Internal Medicine flashcards as text
A 67-year-old man presents with hematuria and a right flank mass. CT shows a 5-cm renal mass with venous thrombus. What is the most likely diagnosis?
Answer: Renal cell carcinoma
Renal cell carcinoma classically presents with hematuria, flank pain, and a palpable mass, and commonly invades the renal vein.
A 50-year-old man with alcohol use disorder presents with acute severe epigastric pain radiating to the back, nausea, and serum lipase 1,200 U/L. Which initial management is most appropriate?
Answer: Aggressive IV fluid resuscitation and NPO
Aggressive early IV fluid resuscitation (preferably with Lactated Ringer's) and bowel rest are the cornerstones of acute pancreatitis management.
A 38-year-old woman with fatigue, proximal muscle weakness, and a heliotrope rash is found to have elevated CK and aldolase. What is the diagnosis?
Answer: Dermatomyositis
Heliotrope rash with proximal muscle weakness and elevated muscle enzymes is diagnostic of dermatomyositis.
A 70-year-old man on warfarin for atrial fibrillation presents with sudden-onset severe headache and altered consciousness. CT shows hyperdense blood in ventricles. INR is 3.8. What is the most urgent reversal agent?
Answer: 4-factor prothrombin complex concentrate (PCC)
4-factor PCC provides the fastest and most complete reversal of warfarin in life-threatening bleeding and is superior to FFP for this indication.
A 55-year-old woman with celiac disease presents with fatigue and macrocytic anemia. She adheres to a gluten-free diet. Which deficiency is most likely contributing?
Answer: Folate deficiency
Celiac disease causes malabsorption in the proximal small intestine where folate is predominantly absorbed, leading to folate-deficiency macrocytic anemia.
A 58-year-old man with stable angina on metoprolol and aspirin develops worsening symptoms despite optimal medical therapy. Stress test shows significant reversible ischemia. What is the next step?
Answer: Coronary angiography
Significant reversible ischemia on non-invasive testing despite optimal medical therapy is an indication for coronary angiography to assess for revascularization.
A 34-year-old woman with recurrent sinopulmonary infections and diarrhea is found to have undetectable serum IgA, IgG, and IgM. B cell count is very low. What is the most likely diagnosis?
Answer: X-linked agammaglobulinemia (Bruton's disease)
X-linked agammaglobulinemia causes near-absent B cells and all immunoglobulin classes due to a BTK gene mutation, presenting with recurrent bacterial infections.