NBE Transthoracic Echocardiography 5 — Questions and Answers
Question 1: Which TTE finding is characteristic of an ostium secundum atrial septal defect (ASD)?
- Dropout in the inlet atrial septum with left-to-right shunt
- Dropout in the fossa ovalis region with right ventricular volume overload (Correct answer)
- Hypermobile atrial septum without shunting
- Premature closure of the foramen ovale
Correct answer: Dropout in the fossa ovalis region with right ventricular volume overload
Ostium secundum ASD appears as a central defect in the fossa ovalis with left-to-right shunting and consequent RV volume overload on TTE.
Question 2: In a patient with dilated cardiomyopathy, which diastolic pattern on mitral inflow Doppler is associated with the worst prognosis?
- Impaired relaxation pattern (E/A < 1)
- Pseudonormal pattern (E/A 1–2)
- Restrictive filling pattern (E/A > 2, short DT) (Correct answer)
- Normal filling pattern (E/A 1–2, normal DT)
Correct answer: Restrictive filling pattern (E/A > 2, short DT)
A restrictive filling pattern (E/A > 2, deceleration time < 150 ms) in DCM indicates severely elevated filling pressures and portends the poorest prognosis.
Question 3: Which condition is most likely when TTE reveals a linear echogenic structure in the right atrium moving independently of the atrial walls?
- Atrial thrombus
- Chiari network or Eustachian valve variant (Correct answer)
- Pacemaker lead perforation
- Right atrial myxoma
Correct answer: Chiari network or Eustachian valve variant
A Chiari network is a remnant of the right valve of the sinus venosus — a mobile, filamentous structure in the RA that is a normal variant.
Question 4: When performing TTE on a patient post-cardiac surgery with a prosthetic mechanical mitral valve, which Doppler parameter is most useful for detecting valve obstruction?
- Peak transmitral velocity and pressure half-time (Correct answer)
- Color Doppler regurgitant jet area
- Tissue Doppler of the mitral annulus
- M-mode of the posterior leaflet
Correct answer: Peak transmitral velocity and pressure half-time
Elevated peak transmitral velocity and prolonged PHT (≥ 130 ms) indicate increased resistance across the prosthetic valve, suggesting obstruction or pannus.
Question 5: Which echocardiographic criterion is used to define a positive bubble study (agitated saline contrast) for patent foramen ovale (PFO)?
- Any bubble appearing in the left heart within 5 cardiac cycles
- ≥ 3 bubbles in the left heart within 3 cardiac cycles of right atrial opacification (Correct answer)
- Bubbles appearing only during Valsalva maneuver
- Continuous left-to-right bubble transit
Correct answer: ≥ 3 bubbles in the left heart within 3 cardiac cycles of right atrial opacification
A positive bubble study for PFO requires ≥ 3 microbubbles appearing in the left heart within 3 cardiac cycles of right atrial opacification, especially with Valsalva.
Question 6: A patient has an aortic stenosis with a mean gradient of 45 mmHg but a calculated AVA of 0.7 cm². LVEF is 35%. This scenario is best described as:
- Moderate aortic stenosis with preserved EF
- Classic severe aortic stenosis
- Low-flow, low-gradient severe aortic stenosis (Correct answer)
- Pseudo-severe aortic stenosis
Correct answer: Low-flow, low-gradient severe aortic stenosis
Low EF reduces stroke volume and transvalvular flow, underestimating the gradient despite a truly small AVA — this is low-flow, low-gradient severe AS.
Question 7: Which TTE view provides the best assessment of the right ventricular free wall for arrhythmogenic right ventricular cardiomyopathy (ARVC)?
- Apical four-chamber (Correct answer)
- Parasternal long-axis
- Subcostal four-chamber
- Suprasternal notch view
Correct answer: Apical four-chamber
The apical four-chamber view offers the longest axis of the RV free wall, enabling detection of dilation, wall motion abnormalities, and aneurysms seen in ARVC.
Which TTE finding is characteristic of an ostium secundum atrial septal defect (ASD)?