NBDHE NBDHE Pharmacology in Dental Hygiene 4

Question 1

A patient on chronic SSRI therapy undergoing periodontal surgery should be monitored for which drug interaction if an NSAID is prescribed post-operatively?

Accepted Answer

Increased risk of GI bleeding due to synergistic platelet inhibition

Answer

SSRIs inhibit platelet serotonin uptake, impairing aggregation; NSAIDs also inhibit platelets, creating a synergistic risk of GI and post-operative bleeding.

Question 2

Epinephrine in local anesthetic solutions is classified as which type of adrenergic agonist?

Accepted Answer

Non-selective alpha and beta agonist

Answer

Epinephrine stimulates both alpha (vasoconstriction) and beta (cardiac stimulation, bronchodilation) adrenergic receptors in a non-selective manner.

Question 3

Which benzodiazepine reversal agent should be available when oral sedation with triazolam is used in the dental office?

Accepted Answer

Flumazenil

Answer

Flumazenil is a competitive benzodiazepine receptor antagonist used to reverse CNS depression caused by benzodiazepines such as triazolam.

Question 4

A nursing mother requires antibiotic therapy for a dental infection. Which drug is considered safest with minimal transfer to breast milk?

Accepted Answer

Amoxicillin

Answer

Amoxicillin has low transfer to breast milk and is generally considered safe for nursing mothers, unlike tetracycline or fluoroquinolones which are contraindicated.

Question 5

A patient taking monoamine oxidase inhibitors (MAOIs) requires dental care. Which drug combination poses the greatest risk?

Accepted Answer

Lidocaine with epinephrine

Answer

Epinephrine combined with MAOIs can cause a hypertensive crisis because MAOIs inhibit the breakdown of catecholamines, amplifying sympathomimetic effects.

NBDHE Test Practice Test

NBDHE Test Practice Test

NBDHE NBDHE Pharmacology in Dental Hygiene 4