NBDHE NBDHE Pharmacology in Dental Hygiene 2

Question 1

A patient taking warfarin requires scaling and root planing. Which drug interaction poses the greatest bleeding risk if prescribed concurrently?

Accepted Answer

Ibuprofen

Answer

Ibuprofen inhibits platelet aggregation and displaces warfarin from plasma proteins, significantly increasing bleeding risk.

Question 2

Which vasoconstrictor is contraindicated in patients taking nonselective beta-blockers due to risk of hypertensive crisis?

Accepted Answer

Levonordefrin

Answer

Levonordefrin (neo-cobefrin) is an alpha-agonist that can cause severe hypertension when combined with nonselective beta-blockers because beta-2 vasodilation is blocked.

Question 3

A patient reports taking sildenafil for pulmonary hypertension. Which drug used in dental emergencies is absolutely contraindicated?

Accepted Answer

Nitroglycerin

Answer

Nitroglycerin combined with sildenafil (a PDE-5 inhibitor) causes profound, potentially fatal hypotension.

Question 4

Bisphosphonate-associated osteonecrosis of the jaw (BRONJ) most commonly occurs in patients taking which form of bisphosphonate therapy?

Accepted Answer

IV zoledronic acid for cancer

Answer

IV bisphosphonates used in oncology carry a significantly higher risk of BRONJ than oral bisphosphonates used for osteoporosis.

Question 5

Which antibiotic prophylaxis regimen is currently recommended by the AHA for a cardiac patient unable to take oral medications?

Accepted Answer

IM cefazolin 2 g or ceftriaxone 1 g

Answer

Current AHA guidelines recommend IM/IV cefazolin 2 g or ceftriaxone 1 g for patients who cannot take oral medications and are not allergic to penicillin.

NBDHE Test Practice Test

NBDHE Test Practice Test

NBDHE NBDHE Pharmacology in Dental Hygiene 2