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Veterinary Pharmacology Flashcards

7 cards from real NAVLE practice questions. Tap to flip, then mark Knew It or Still Learning — missed cards come back until you master them.

Read the first 7 Veterinary Pharmacology flashcards as text

  1. Which opioid analgesic is commonly used in cats but must be used cautiously due to their limited glucuronidation capacity?

    Answer: Buprenorphine

    Buprenorphine is preferred in cats because its partial agonist activity and high mu-receptor affinity make it effective at lower doses, reducing the risk of adverse effects from impaired glucuronidation.

  2. A dog is prescribed phenobarbital for seizure control. Which of the following is the most important monitoring parameter for long-term therapy?

    Answer: Serum bile acids and liver enzymes

    Phenobarbital induces hepatic enzymes and can cause hepatotoxicity with long-term use, so serum bile acids and liver enzymes must be monitored regularly.

  3. Which drug class is contraindicated in cats due to their deficiency in UDP-glucuronosyltransferase?

    Answer: NSAIDs metabolized via glucuronidation

    Cats lack sufficient UDP-glucuronosyltransferase activity, making drugs like acetaminophen and certain NSAIDs dependent on glucuronidation highly toxic.

  4. A horse develops laminitis after prolonged use of which drug class?

    Answer: Corticosteroids

    Prolonged corticosteroid use in horses can lead to laminitis due to alterations in digital blood flow and carbohydrate metabolism.

  5. Which antimicrobial is most appropriate for treating Rhodococcus equi pneumonia in foals?

    Answer: Rifampin combined with azithromycin or clarithromycin

    Rifampin combined with a macrolide (azithromycin or clarithromycin) is the standard of care for Rhodococcus equi because the combination achieves good intracellular penetration.

  6. What is the mechanism of action of metronidazole in treating anaerobic infections?

    Answer: Disrupts DNA via reductive activation forming free radicals

    Metronidazole undergoes reductive activation in anaerobic organisms, forming cytotoxic free radicals that disrupt DNA structure and function.

  7. A rabbit is brought in with GI stasis. Which analgesic is safest to use in rabbits?

    Answer: Meloxicam

    Meloxicam is the preferred NSAID in rabbits and is commonly used for pain management due to its established safety profile in this species.