NAVLE Veterinary Pharmacology Questions and Answers

Question 1

A veterinarian treats a group of feeder calves for bovine respiratory disease (BRD) with enrofloxacin.
What is the primary reason for the strict prohibition of extra-label use of this drug in food-producing animals?

Accepted Answer

It promotes the development of antimicrobial resistance in human pathogens.

Answer

It causes severe and irreversible nephrotoxicity in cattle.

Answer

It causes permanent discoloration of meat products.

Answer

There is a high risk of fatal anaphylactic reactions in human consumers.

Question 2

Which of the following antiparasitic drugs has a narrow margin of safety and is associated with severe neurotoxicity in dog breeds with the ABCB1 (formerly MDR1) gene mutation, such as Collies and Australian Shepherds?

Accepted Answer

Ivermectin

Answer

Fipronil

Answer

Praziquantel

Answer

Selamectin

Question 3

A 4-year-old cat requires post-operative analgesia following a routine ovariohysterectomy. Considering feline-specific metabolism and safety profiles, which of the following NSAIDs is licensed and generally considered a safer short-term option for this patient?

Accepted Answer

Robenacoxib

Answer

Carprofen

Answer

Acetaminophen

Answer

Phenylbutazone

Question 4

Which of the following medications is a potent, broad-spectrum antiemetic that functions by antagonizing neurokinin-1 (NK-1) receptors in the central vomiting center?

Accepted Answer

Maropitant

Answer

Ondansetron

Answer

Metoclopramide

Answer

Famotidine

Question 5

A dog is presented with acute onset of severe muscle tremors, hypersalivation, and miosis after potential exposure to a pesticide. Organophosphate toxicity is suspected. Which combination of drugs is the most appropriate treatment to counteract both the muscarinic and nicotinic effects?

Accepted Answer

Atropine and Pralidoxime (2-PAM)

Answer

Diazepam and Fomepizole

Answer

Vitamin K1 and Methocarbamol

Answer

Naloxone and Epinephrine

Question 6

A veterinarian administers detomidine to a horse for standing sedation. This drug produces reliable sedation, muscle relaxation, and analgesia by acting as a potent agonist at which of the following receptors?

Accepted Answer

Alpha-2 adrenergic receptor

Answer

Mu-opioid receptor

Answer

NMDA receptor

Answer

GABA receptor

A veterinarian treats a group of feeder calves for bovine respiratory disease (BRD) with enrofloxacin.What is the primary reason for the strict prohibition of extra-label use of this drug in food-producing animals?

A veterinarian treats a group of feeder calves for bovine respiratory disease (BRD) with enrofloxacin.
What is the primary reason for the strict prohibition of extra-label use of this drug in food-producing animals?