Veterinary Pharmacology Flashcards
7 cards from real NAVLE practice questions. Tap to flip, then mark Knew It or Still Learning — missed cards come back until you master them.
Read the first 7 Veterinary Pharmacology flashcards as text
A dog receives an overdose of acepromazine. Which statement about acepromazine reversal is correct?
Answer: There is no specific reversal agent; treatment is supportive
Acepromazine, a phenothiazine tranquilizer, has no specific reversal agent; management consists of supportive care including IV fluids and vasopressors for hypotension.
Which class of drugs can cause crystalluria and urinary obstruction in dogs, particularly in acidic urine?
Answer: Sulfonamides
Sulfonamides can precipitate in acidic urine and form crystals, potentially causing crystalluria, hematuria, and renal tubular obstruction.
A cattle producer wants to treat a cow with bacterial pneumonia. Which beta-lactam antibiotic has an approved long-acting formulation for cattle?
Answer: Ceftiofur
Ceftiofur (as ceftiofur crystalline free acid) has a long-acting formulation approved in cattle that provides therapeutic concentrations for several days.
What is the primary concern when using ketamine as the sole anesthetic in a dog?
Answer: Inadequate muscle relaxation and increased muscle tone
Ketamine alone causes increased muscle tone and catalepsy rather than muscle relaxation, so it is typically combined with a benzodiazepine or alpha-2 agonist for adequate relaxation.
Which drug used in cattle to synchronize estrus can cause luteolysis by acting on the corpus luteum?
Answer: Prostaglandin F2α (PGF2α)
Prostaglandin F2α causes regression of the corpus luteum (luteolysis), leading to a decrease in progesterone and allowing the next follicular wave to result in estrus.
Which antifungal drug works by inhibiting the enzyme lanosterol 14-alpha-demethylase, disrupting ergosterol synthesis?
Answer: Fluconazole
Fluconazole (and other azole antifungals) inhibit lanosterol 14-alpha-demethylase, blocking ergosterol synthesis and disrupting fungal cell membrane integrity.
A dog with dilated cardiomyopathy is started on digoxin. Which electrolyte abnormality increases the risk of digoxin toxicity?
Answer: Hypokalemia
Hypokalemia potentiates digoxin toxicity because potassium and digoxin compete for the same binding site on Na+/K+-ATPase; low potassium increases digoxin binding and effect.