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Feline Pharmacology and Toxicology Flashcards

7 cards from real NAVLE practice questions. Tap to flip, then mark Knew It or Still Learning — missed cards come back until you master them.

Read the first 7 Feline Pharmacology and Toxicology flashcards as text

  1. A cat presents with sedation, hypersalivation, and ataxia after grooming itself following topical permethrin application intended for dogs. What is the most appropriate treatment?

    Answer: Bathe with mild dish soap and provide supportive care including muscle relaxants

    Permethrin toxicity in cats causes neurological signs; bathing removes the toxin and methocarbamol or diazepam controls tremors.

  2. Which fluoroquinolone antibiotic is most associated with acute retinal degeneration and blindness in cats when used at high doses?

    Answer: Enrofloxacin

    Enrofloxacin at doses above 5 mg/kg/day causes retinal degeneration in cats due to accumulation in the retinal pigment epithelium.

  3. A cat is prescribed methimazole for hyperthyroidism. Which adverse effect is most commonly reported in the first 1–3 months of therapy?

    Answer: Facial pruritus and excoriation

    Facial pruritus, excoriation, and self-induced facial lesions are the most common early adverse effects of methimazole in cats.

  4. Lily (Lilium spp.) ingestion in cats primarily targets which organ system?

    Answer: Renal system

    True lily ingestion in cats causes acute renal failure due to nephrotoxic steroidal glycosides; even small amounts can be fatal.

  5. When using buprenorphine in cats, which route of administration achieves good bioavailability due to the cat's naturally alkaline oral pH?

    Answer: Transmucosal (sublingual/buccal)

    The alkaline oral pH of cats promotes ionization of buprenorphine at mucosal surfaces, giving transmucosal administration ~100% bioavailability.

  6. A cat ingests mouse bait containing brodifacoum. How long after ingestion can clinical signs of coagulopathy be expected?

    Answer: 3–5 days

    Brodifacoum depletes vitamin K-dependent clotting factors; signs appear after existing factors are consumed, typically 3–5 days post-ingestion.

  7. Which drug class is contraindicated in cats with urethral obstruction due to risk of worsening urethral tone?

    Answer: Opioid agonists

    Pure opioid agonists (e.g., morphine) increase urethral sphincter tone in cats and can worsen urinary obstruction.