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Feline Infectious Flashcards

7 cards from real NAVLE practice questions. Tap to flip, then mark Knew It or Still Learning — missed cards come back until you master them.

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  1. What is the gold standard diagnostic test for confirming wet (effusive) FIP?

    Answer: Effusion fluid RT-PCR for FCoV with immunostaining of macrophages

    Immunostaining for FCoV antigen within macrophages in effusion fluid or tissue biopsy is the gold standard for definitive FIP diagnosis.

  2. Feline leukemia virus (FeLV) is classified into subtypes based on host range. Which subtype is associated with the most rapid disease progression and immunosuppression?

    Answer: FeLV-T

    FeLV-T is highly pathogenic, targets T lymphocytes directly causing profound lymphopenia and accelerated immunodeficiency.

  3. A kitten born to a queen with Toxoplasma gondii primary infection during pregnancy is most at risk for which clinical outcome?

    Answer: Fading kitten syndrome with hepatic necrosis

    Congenitally infected kittens develop severe disseminated toxoplasmosis with hepatic necrosis, often presenting as fading kittens.

  4. Which test best differentiates a vaccinated cat from a truly FeLV-infected cat when using a standard ELISA?

    Answer: The ELISA detects p27 antigen which vaccines do not induce

    FeLV ELISA tests detect the p27 core antigen released by replicating virus, not antibody, so vaccination does not produce a positive result.

  5. A cat is diagnosed with feline infectious anemia caused by Mycoplasma haemofelis. Which treatment is most appropriate?

    Answer: Doxycycline with supportive care including blood transfusion if needed

    Doxycycline is the first-line antibiotic for Mycoplasma haemofelis, with blood transfusion reserved for severely anemic cats.

  6. Feline infectious peritonitis dry (non-effusive) form most commonly causes granulomatous lesions in which anatomical sites?

    Answer: Eyes, CNS, and abdominal organs

    Dry FIP granulomas typically affect the eyes (uveitis), CNS (ataxia, seizures), and abdominal organs (kidney, mesenteric lymph nodes).

  7. GS-441524, the active metabolite of remdesivir, has shown efficacy against FIP by targeting which viral component?

    Answer: Viral RNA-dependent RNA polymerase

    GS-441524 is a nucleoside analog that inhibits the RNA-dependent RNA polymerase of feline coronavirus, blocking viral replication.