NATA-BOC Pharmacology and Drug Management Flashcards
6 cards from real NATA-BOC practice questions. Tap to flip, then mark Knew It or Still Learning — missed cards come back until you master them.
Read the first 6 NATA-BOC Pharmacology and Drug Management flashcards as text
What is the mechanism by which acetaminophen reduces pain?
Answer: Acting centrally to raise the pain threshold
Acetaminophen works primarily through central mechanisms, raising the pain threshold in the brain rather than reducing peripheral inflammation.
An athlete with a known sulfa allergy reports taking a diuretic. Which diuretic class should be avoided due to cross-reactivity?
Answer: Thiazide diuretics
Thiazide diuretics contain a sulfonamide group and can cross-react in patients with sulfa allergies, making them potentially unsafe.
What is the recommended maximum daily dose of acetaminophen for a healthy adult to prevent hepatotoxicity?
Answer: 4,000 mg
The FDA recommends a maximum of 4,000 mg of acetaminophen per day for healthy adults to avoid liver toxicity.
Which term describes the phase of drug metabolism where a drug is converted into a water-soluble form for renal excretion?
Answer: Phase II metabolism
Phase II metabolism involves conjugation reactions (e.g., glucuronidation) that make metabolites water-soluble for urinary excretion.
An athletic trainer is advising a female athlete on iron supplementation. Which co-ingestion enhances non-heme iron absorption?
Answer: Vitamin C
Vitamin C (ascorbic acid) reduces non-heme iron to its ferrous form, significantly enhancing its absorption in the gastrointestinal tract.
What is the primary organ responsible for drug metabolism in the body?
Answer: Liver
The liver is the primary site of drug metabolism, using cytochrome P450 enzymes to biotransform drugs into metabolites for elimination.