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Therapeutic Plan Assessment Flashcards

7 cards from real NAPLEX QBANK practice questions. Tap to flip, then mark Knew It or Still Learning — missed cards come back until you master them.

Read the first 7 Therapeutic Plan Assessment flashcards as text

  1. A patient with major depression has failed an adequate trial of one SSRI. What is the most appropriate next step?

    Answer: Switch to another antidepressant or augment

    After an adequate but inadequate SSRI trial, switching agents or augmenting is the guideline-based next step.

  2. A patient on a statin reports new muscle pain and the CK is markedly elevated. What is the priority intervention?

    Answer: Discontinue the statin and assess for rhabdomyolysis

    Marked CK elevation with myalgia suggests statin myopathy or rhabdomyolysis, requiring drug discontinuation.

  3. Which agent should be avoided in a patient with a sulfa allergy who needs a diuretic, when caution is warranted?

    Answer: Hydrochlorothiazide

    Thiazides contain a sulfonamide moiety and warrant caution in patients with sulfa hypersensitivity.

  4. A patient on a DOAC needs an urgent reversal before emergency surgery. Which reversal agent matches dabigatran?

    Answer: Idarucizumab

    Idarucizumab is the specific reversal agent for the direct thrombin inhibitor dabigatran.

  5. A patient with gout on chronic urate-lowering therapy has frequent flares during initiation. What preventive plan is appropriate?

    Answer: Add anti-inflammatory flare prophylaxis such as colchicine

    Flare prophylaxis with colchicine or NSAIDs is recommended when starting urate-lowering therapy.

  6. A patient with atrial fibrillation and a CHA2DS2-VASc score of 4 is currently on aspirin only. What is the appropriate therapeutic change?

    Answer: Start oral anticoagulation

    A CHA2DS2-VASc score of 4 warrants oral anticoagulation rather than aspirin for stroke prevention.

  7. A patient taking an ACE inhibitor develops a persistent dry cough without angioedema. What is the best alternative?

    Answer: Switch to an ARB

    ACE inhibitor-induced cough is bradykinin-mediated, and switching to an ARB avoids it while preserving RAAS blockade.