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Practice Test Flashcards

7 cards from real NAPLEX QBANK practice questions. Tap to flip, then mark Knew It or Still Learning — missed cards come back until you master them.

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  1. A patient on warfarin needs an antibiotic. Which choice carries the HIGHEST risk of increasing INR?

    Answer: Trimethoprim-sulfamethoxazole

    Trimethoprim-sulfamethoxazole inhibits CYP2C9 and displaces warfarin from protein, markedly raising INR.

  2. Which counseling point is essential for a patient starting alendronate?

    Answer: Take with at least 6 oz water and remain upright 30 minutes

    Bisphosphonates must be taken with plain water on an empty stomach, staying upright to prevent esophageal irritation.

  3. A patient with hyperkalemia (K 6.2) and ECG changes should first receive which agent to stabilize the myocardium?

    Answer: Calcium gluconate

    IV calcium gluconate stabilizes the cardiac membrane immediately, even though it does not lower potassium.

  4. Which statin requires the most caution when combined with gemfibrozil due to rhabdomyolysis risk?

    Answer: Simvastatin

    Gemfibrozil is contraindicated with simvastatin because it greatly increases statin exposure and myopathy risk.

  5. What is the antidote for acetaminophen overdose?

    Answer: N-acetylcysteine

    N-acetylcysteine replenishes glutathione to detoxify the toxic NAPQI metabolite.

  6. Which medication should be held before iodinated contrast in a patient with renal impairment due to lactic acidosis risk?

    Answer: Metformin

    Metformin is held around contrast administration in renal impairment because of lactic acidosis risk.

  7. A patient develops a dry cough on lisinopril. The best alternative within RAAS blockade is:

    Answer: Losartan

    An ARB like losartan avoids the bradykinin-mediated cough seen with ACE inhibitors while keeping RAAS blockade.