Respiratory Disease Management Flashcards
7 cards from real MTM practice questions. Tap to flip, then mark Knew It or Still Learning — missed cards come back until you master them.
Read the first 7 Respiratory Disease Management flashcards as text
A patient prescribed an inhaled corticosteroid (ICS) for asthma asks how to prevent oral candidiasis. What is the MOST effective counseling point?
Answer: Rinse the mouth and gargle with water after each use
Rinsing the mouth and gargling after ICS use removes residual drug from the oropharynx, significantly reducing the risk of oral candidiasis.
Which respiratory medication requires monitoring of serum drug levels due to its narrow therapeutic index?
Answer: Theophylline
Theophylline has a narrow therapeutic index (target 5-15 mcg/mL) and requires regular serum level monitoring to ensure efficacy and avoid toxicity.
A COPD patient on triple therapy reports increased dyspnea and purulent yellow-green sputum for 3 days. This presentation is MOST consistent with:
Answer: Acute COPD exacerbation
Increased dyspnea with change in sputum character (volume or purulence) beyond normal day-to-day variation is the hallmark of an acute COPD exacerbation.
When counseling a patient about proper dry powder inhaler (DPI) technique, the pharmacist should emphasize:
Answer: Rapid, forceful inhalation through the device
DPIs require rapid, forceful inhalation to generate sufficient turbulent airflow to disaggregate and deliver the powder to the lower airways.
Which biologic agent targets the IL-4/IL-13 pathway and is FDA-approved for moderate-to-severe eosinophilic or OCS-dependent asthma?
Answer: Dupilumab (anti-IL-4Rα)
Dupilumab blocks the IL-4Rα receptor, inhibiting both IL-4 and IL-13 signaling, and is approved for moderate-to-severe asthma and other type 2 inflammatory conditions.
A patient has allergic asthma with serum IgE of 450 IU/mL, positive allergen skin testing, and remains uncontrolled on high-dose ICS/LABA. Which biologic is MOST appropriate?
Answer: Omalizumab (anti-IgE)
Omalizumab targets free IgE and is specifically indicated for allergic asthma in patients with elevated IgE (30-700 IU/mL) and confirmed allergen sensitization.
Which statement about pulmonary rehabilitation in COPD is MOST accurate?
Answer: It improves exercise capacity and quality of life but has not been shown to reduce mortality
Pulmonary rehabilitation consistently improves exercise tolerance, dyspnea, and health-related quality of life in COPD but has not demonstrated a mortality benefit.