MPH Epidemiology & Biostatistics 1 — Questions and Answers
Question 1: What does 'incidence rate' measure in epidemiology?
- The number of new cases in a population over a time period (Correct answer)
- The total number of existing cases at a point in time
- The proportion of deaths among those diagnosed
- The rate of recovery from a disease
Correct answer: The number of new cases in a population over a time period
Incidence rate measures new cases occurring in a defined population during a specified time period.
Question 2: Which study design is considered the gold standard for establishing causality?
- Cross-sectional study
- Case-control study
- Randomized controlled trial (Correct answer)
- Cohort study
Correct answer: Randomized controlled trial
Randomized controlled trials are considered the gold standard because randomization minimizes confounding and allows causal inference.
Question 3: A p-value of 0.03 means:
- There is a 3% chance the null hypothesis is true
- There is a 97% chance the alternative hypothesis is true
- There is a 3% probability of observing results as extreme as these if the null hypothesis is true (Correct answer)
- The study has 97% power
Correct answer: There is a 3% probability of observing results as extreme as these if the null hypothesis is true
A p-value represents the probability of observing results at least as extreme as those found, assuming the null hypothesis is true.
Question 4: What is a confidence interval used for in public health research?
- To determine if a study is ethical
- To estimate the range within which the true population parameter likely falls (Correct answer)
- To calculate sample size requirements
- To adjust for confounding variables
Correct answer: To estimate the range within which the true population parameter likely falls
A confidence interval provides a range of plausible values for the true population parameter based on the sample data.
Question 5: Which measure of disease frequency is most appropriate for chronic diseases with long duration?
- Incidence rate
- Attack rate
- Prevalence (Correct answer)
- Case fatality rate
Correct answer: Prevalence
Prevalence captures all existing cases at a point in time, making it more useful for chronic conditions that persist over time.
Question 6: Relative risk (RR) of 1.0 indicates:
- A strong positive association
- No association between exposure and outcome (Correct answer)
- A strong negative association
- The study was underpowered
Correct answer: No association between exposure and outcome
An RR of 1.0 means the risk in the exposed group equals the risk in the unexposed group, indicating no association.
What does 'incidence rate' measure in epidemiology?