Practice Test Geeks(MLS) Medical Laboratory Scientist Practice Test
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Blood Banking & Transfusion Medicine Flashcards

7 cards from real MLS practice questions. Tap to flip, then mark Knew It or Still Learning — missed cards come back until you master them.

Read the first 7 Blood Banking & Transfusion Medicine flashcards as text

  1. Which blood type is considered the universal donor for packed red blood cells?

    Answer: O negative

    O negative red blood cells lack A, B, and Rh D antigens, making them compatible with recipients of any blood type.

  2. A patient with Type A blood has which naturally occurring antibody in their serum?

    Answer: Anti-B

    Type A individuals produce Anti-B antibodies per Landsteiner's rule, which states that individuals form antibodies against ABO antigens they do not possess.

  3. Which crossmatch method is most sensitive for detecting clinically significant alloantibodies?

    Answer: Antiglobulin (indirect) crossmatch

    The antiglobulin (indirect) crossmatch detects IgG antibodies and complement that coat red cells without immediate agglutination, identifying clinically significant antibodies capable of causing hemolysis.

  4. A positive Direct Antiglobulin Test (DAT) indicates that:

    Answer: The patient's red blood cells are coated with IgG or complement in vivo

    A positive DAT demonstrates that the patient's circulating red blood cells are sensitized (coated) with IgG antibodies or complement components in vivo.

  5. At what temperature and conditions must platelets be stored in the blood bank?

    Answer: 20–24°C with continuous gentle agitation

    Platelets must be stored at 20–24°C with continuous gentle agitation to maintain metabolic activity, pH, and prevent platelet clumping.

  6. Which Rh antigen is considered the most clinically significant and immunogenic?

    Answer: Rh D

    The D antigen is the most immunogenic of the Rh antigens and is the primary antigen responsible for hemolytic disease of the fetus and newborn (HDFN) and hemolytic transfusion reactions.

  7. Which blood type is the universal recipient for packed red blood cells?

    Answer: AB positive

    AB positive individuals have A, B, and D antigens on their red cells and no ABO antibodies in serum, allowing them to receive red cells from any ABO/Rh blood group.