MLPAO Hematology and Coagulation Advanced Practice

Question 1

What is the significance of Auer rods found on a peripheral blood smear?

Accepted Answer

They are pathognomonic for acute myeloid leukemia

Answer

They indicate viral infection

Answer

They suggest iron overload

Answer

They indicate vitamin B12 deficiency

Question 2

Which hematological malignancy is associated with the Philadelphia chromosome t(9;22)?

Accepted Answer

Chronic myeloid leukemia (CML)

Answer

Acute lymphoblastic leukemia

Answer

Hodgkin lymphoma

Answer

Multiple myeloma

Question 3

What is the principle of flow cytometry immunophenotyping in hematological malignancies?

Accepted Answer

Identifying cell surface and intracellular markers using fluorescent-labeled antibodies

Answer

Measuring cell size by impedance

Answer

Staining cells with Romanowsky dyes

Answer

Counting cells based on nuclear morphology

Question 4

Which condition is characterized by a markedly elevated white blood cell count with a predominance of mature lymphocytes in an elderly patient?

Accepted Answer

Chronic lymphocytic leukemia (CLL)

Answer

Acute myeloid leukemia

Answer

Infectious mononucleosis

Answer

Chronic myeloid leukemia

Question 5

What is heparin-induced thrombocytopenia (HIT) type II?

Accepted Answer

An immune-mediated condition causing platelet activation, thrombocytopenia, and paradoxical thrombosis

Answer

A benign, transient drop in platelets within the first 2 days of heparin

Answer

An allergic reaction to heparin causing rash

Answer

A genetic platelet disorder worsened by heparin

Question 6

Which laboratory test is used to monitor direct oral anticoagulants (DOACs) when needed?

Accepted Answer

Anti-Xa assay for rivaroxaban/apixaban; dilute thrombin time for dabigatran

Answer

PT/INR for all DOACs

Answer

aPTT for all DOACs

Answer

Fibrinogen assay