Oral & Dental Pathology Flashcards
6 cards from real MJDF practice questions. Tap to flip, then mark Knew It or Still Learning — missed cards come back until you master them.
Read the first 6 Oral & Dental Pathology flashcards as text
What investigation is used to diagnose pemphigus vulgaris affecting the oral mucosa?
Answer: Perilesional biopsy with direct immunofluorescence showing IgG intercellular pattern
Direct immunofluorescence (DIF) of perilesional tissue showing IgG (and sometimes complement) deposits in a 'chicken wire' intercellular pattern of the epithelium is diagnostic of pemphigus vulgaris.
What is the most common pre-malignant condition of the lip?
Answer: Actinic cheilitis
Actinic cheilitis (solar keratosis of the lip) results from chronic UV exposure and is the most common premalignant lip condition, particularly affecting fair-skinned individuals on the lower lip.
Which finding on clinical examination of the oral mucosa is most associated with carcinoma in situ?
Answer: Speckled (non-homogeneous) erythroleukoplakia — red and white mixed lesion
Speckled erythroleukoplakia (mixed red and white areas) has the highest rate of dysplasia and carcinoma in situ at presentation among oral potentially malignant disorders.
What is the histological composition of an ameloblastoma?
Answer: Follicular or plexiform patterns of odontogenic epithelium with central stellate reticulum-like areas
Ameloblastoma shows follicular (islands with central stellate reticulum-like cells) or plexiform (network of anastomosing cords) patterns of odontogenic epithelium with peripheral columnar ameloblast-like cells.
What is the most common jaw cyst overall?
Answer: Radicular cyst (periapical cyst)
Radicular cysts (periapical cysts) are the most common jaw cysts, accounting for approximately 52–68% of all jaw cysts, arising from epithelial rests of Malassez activated by periapical inflammation.
What is the pathological mechanism underlying dry socket (alveolar osteitis)?
Answer: Premature fibrinolysis of the blood clot leading to exposed, infected alveolar bone
Dry socket results from fibrinolysis (bacterial plasminogen activators dissolve the clot) or mechanical dislodgement, leaving bare alveolar bone exposed to oral bacteria and debris, causing severe pain.