MFDS Pharmacology 3

Question 1

Which corticosteroid preparation is most appropriate for topical treatment of oral mucosal lesions?

Accepted Answer

All are appropriate depending on severity

Answer

Hydrocortisone pellets

Answer

Betamethasone mouthwash

Answer

Clobetasol propionate ointment

Question 2

Carbamazepine is the drug of first choice for management of:

Accepted Answer

Trigeminal neuralgia

Answer

Burning mouth syndrome

Answer

Atypical facial pain

Answer

Temporomandibular disorders

Question 3

The mechanism of action of chlorhexidine as an antiseptic mouthwash is:

Accepted Answer

Disruption of bacterial cell membranes

Answer

Inhibition of cell wall synthesis

Answer

Inhibition of DNA gyrase

Answer

Competitive inhibition of folic acid synthesis

Question 4

Erythromycin achieves its antibacterial effect by binding to the:

Accepted Answer

50S ribosomal subunit

Answer

30S ribosomal subunit

Answer

DNA gyrase

Answer

Penicillin-binding protein

Question 5

Which drug is used prophylactically to prevent infective endocarditis before high-risk dental procedures?

Accepted Answer

NICE guidelines no longer recommend routine antibiotic prophylaxis

Answer

Amoxicillin 3g orally 1 hour before

Answer

Clindamycin 600mg IV during procedure

Answer

Metronidazole 400mg pre-operatively

Question 6

Prednisolone, a synthetic glucocorticoid, suppresses inflammation primarily by:

Accepted Answer

Inducing lipocortin which inhibits phospholipase A2

Answer

Inhibiting COX-2 directly

Answer

Blocking histamine receptors

Answer

Activating mast cell degranulation