MFDS Pharmacology 2

Question 1

Which property of local anaesthetics determines their potency?

Accepted Answer

Lipid solubility

Answer

Protein binding

Answer

pKa

Answer

Molecular weight

Question 2

The onset of action of a local anaesthetic is primarily determined by its:

Accepted Answer

pKa

Answer

Lipid solubility

Answer

Protein binding

Answer

Molecular weight

Question 3

Adrenaline (epinephrine) is added to local anaesthetic solutions primarily to:

Accepted Answer

Cause vasoconstriction and prolong anaesthesia

Answer

Increase patient alertness

Answer

Alkalinise the solution

Answer

Reduce systemic toxicity alone

Question 4

Warfarin anticoagulation should be assessed before dental extractions using:

Accepted Answer

INR

Answer

APTT

Answer

Platelet count

Answer

Bleeding time

Question 5

Tetracyclines are contraindicated in children under 12 years because they:

Accepted Answer

Bind to calcium in developing teeth causing staining

Answer

Cause nephrotoxicity

Answer

Suppress bone marrow

Answer

Cross the blood-brain barrier

Question 6

Which drug interaction is most clinically significant when prescribing metronidazole?

Accepted Answer

Alcohol (disulfiram-like reaction)

Answer

Paracetamol

Answer

Ibuprofen

Answer

Amoxicillin