Pharmacology Flashcards
6 cards from real MFDS practice questions. Tap to flip, then mark Knew It or Still Learning โ missed cards come back until you master them.
Read the first 6 Pharmacology flashcards as text
Articaine differs from other amide local anaesthetics in that it contains:
Answer: A thiophene ring
Articaine uniquely contains a thiophene ring instead of a benzene ring, which increases its lipid solubility and ability to diffuse through bone.
The maximum recommended dose of lidocaine with adrenaline for a healthy adult is approximately:
Answer: 7 mg/kg (max 500 mg)
Lidocaine with adrenaline (epinephrine) has a maximum recommended dose of 7 mg/kg up to 500 mg in healthy adults, higher than plain lidocaine due to vasoconstriction.
Which antibiotic is first-line for odontogenic infections in penicillin-allergic patients?
Answer: Clindamycin
Clindamycin is an appropriate first-line alternative for odontogenic infections in penicillin-allergic patients due to its excellent activity against streptococci and anaerobes.
NSAIDs exert their analgesic effect primarily by inhibiting which enzyme?
Answer: Cyclooxygenase (COX)
NSAIDs inhibit cyclooxygenase (COX-1 and COX-2) enzymes, thereby blocking prostaglandin synthesis and reducing pain, inflammation and fever.
Fluconazole is the drug of choice for treating which oral fungal infection?
Answer: Oropharyngeal candidiasis
Fluconazole, a triazole antifungal, is highly effective and well tolerated for oropharyngeal and oesophageal candidiasis, particularly in immunocompromised patients.
Bisphosphonates inhibit bone resorption primarily by targeting:
Answer: Osteoclasts
Bisphosphonates bind to hydroxyapatite and are taken up by osteoclasts, inhibiting the mevalonate pathway and inducing osteoclast apoptosis.