Mesothelioma Therapy Chemotherapy for Mesothelioma 2

Question 1

What is the most common dose-limiting toxicity of pemetrexed in mesothelioma treatment?

Accepted Answer

Myelosuppression (neutropenia)

Answer

Alopecia

Answer

Peripheral neuropathy

Answer

Hepatotoxicity

Question 2

Cisplatin-based chemotherapy requires adequate pretreatment hydration primarily to prevent which toxicity?

Accepted Answer

Nephrotoxicity (kidney damage)

Answer

Hepatotoxicity

Answer

Cardiotoxicity

Answer

Neurotoxicity

Question 3

Which chemotherapy drug combination was approved for second-line mesothelioma in the US after initial chemotherapy failure?

Accepted Answer

Nivolumab + ipilimumab

Answer

Pemetrexed monotherapy

Answer

Ramucirumab + gemcitabine

Answer

Vinorelbine monotherapy

Question 4

What is the purpose of corticosteroid premedication before pemetrexed infusion?

Accepted Answer

To prevent skin rash

Answer

To enhance anticancer activity

Answer

To reduce nausea

Answer

To improve renal clearance

Question 5

In neoadjuvant chemotherapy for mesothelioma, when is chemotherapy administered relative to surgery?

Accepted Answer

Before surgery

Answer

After surgery

Answer

During surgery

Answer

Only if surgery is refused

Question 6

Which organ function must be closely monitored during cisplatin-based chemotherapy for mesothelioma?

Accepted Answer

Kidneys

Answer

Liver

Answer

Spleen

Answer

Pancreas