Medical Technologist Test Immunology and Serology 2

Question 1

Which hepatitis B serological marker is the FIRST to appear in serum during acute infection?

Accepted Answer

HBsAg

Answer

Anti-HBs

Answer

Anti-HBc IgG

Answer

HBeAg

Question 2

The RPR (Rapid Plasma Reagin) test for syphilis uses which antigen?

Accepted Answer

Cardiolipin-lecithin-cholesterol

Answer

Treponema pallidum lysate

Answer

Purified treponemal protein

Answer

Fluorescent-labeled Treponema

Question 3

The prozone phenomenon in serology results in a false-negative reaction due to:

Accepted Answer

Antibody excess preventing lattice formation

Answer

Antigen excess preventing lattice formation

Answer

Incorrect reaction temperature

Answer

Improper pH of the buffer

Question 4

Which test is used as a CONFIRMATORY assay for HIV infection following a reactive screening result?

Accepted Answer

Western blot

Answer

ELISA

Answer

Rapid plasma reagin

Answer

Particle agglutination

Question 5

C-reactive protein (CRP) is produced primarily by which organ during the acute phase response?

Accepted Answer

Liver

Answer

Spleen

Answer

Bone marrow

Answer

Lymph nodes

Question 6

The Weil-Felix test uses Proteus OX antigen strains to diagnose infections caused by:

Accepted Answer

Rickettsia species

Answer

Brucella species

Answer

Leptospira species

Answer

Borrelia burgdorferi

Question 7

Which complement component is shared by ALL three activation pathways (classical, alternative, and lectin)?

Accepted Answer

C3

Answer

C1q

Answer

Factor B

Answer

MASP-1