Blood Banking Flashcards
6 cards from real Medical Technologist Test practice questions. Tap to flip, then mark Knew It or Still Learning — missed cards come back until you master them.
Read the first 6 Blood Banking flashcards as text
RhoGAM (anti-D immunoglobulin) is administered to Rh-negative mothers to prevent sensitization by doing which of the following?
Answer: Blocking fetal Rh D antigens from sensitizing the mother
RhoGAM binds to fetal Rh D-positive RBCs that entered maternal circulation, preventing them from triggering maternal anti-D alloimmunization.
Which blood group system is most clinically significant after ABO and Rh for causing hemolytic transfusion reactions?
Answer: Kell (K)
Kell system antibodies, particularly anti-K, are strongly immunogenic and clinically significant, causing both hemolytic transfusion reactions and HDFN.
Washed red blood cells are used for patients with which condition to prevent transfusion reactions?
Answer: Severe IgA deficiency with anti-IgA antibodies
IgA-deficient patients with anti-IgA can have anaphylactic reactions to plasma proteins; washing removes IgA from donor blood.
A patient's forward type shows A antigen but reverse typing shows no anti-B antibody. This discrepancy is MOST likely due to which cause?
Answer: Hypogammaglobulinemia causing absent isohemagglutinins
Elderly or immunosuppressed patients with hypogammaglobulinemia may lack expected ABO isohemagglutinins, causing forward-reverse ABO discrepancies.
Which type of transfusion reaction is caused by preformed recipient antibodies against donor HLA or granulocyte antigens?
Answer: Febrile non-hemolytic transfusion reaction (FNHTR)
FNHTR is caused by recipient antibodies reacting with donor leukocyte HLA antigens, releasing cytokines that cause fever and chills during transfusion.
The shelf life of fresh frozen plasma (FFP) stored at –18°C or colder is how long?
Answer: 1 year
FFP stored at –18°C or colder has a shelf life of 1 year; it must be thawed at 30–37°C before use and transfused within 24 hours.