MRO Cheat Sheet 2026

The 30 highest-yield MRO facts, distilled from real exam questions. Print it, save it as a PDF, or study it here — free, no sign-up.

1. Under DOT 49 CFR Part 40, how often must a laboratory submit blind quality control specimens to the HHS-certified laboratory it contracts with? → At least once per month
2. What is the PRIMARY purpose of continuing education requirements in Contract Closeout Procedures for MRO professionals? → Maintaining current knowledge and competency as the field evolves
3. Why is specimen validity testing performed? → To ensure specimen integrity
4. Under DOT regulations, how must the MRO conduct the verification interview with the donor? → By telephone or in person, on a confidential basis
5. Which practice BEST supports MRO quality assurance when reviewing cancelled test results? → Document the reason for cancellation and trend cancelled tests over time
6. Under DOT regulations, an MRO is required to retain records of verified positive, adulterated, and substituted results for a minimum of: → Five years
7. An MRO self-audit reveals that employee interview documentation is inconsistent across cases. The BEST corrective action is to: → Develop a standardized interview checklist and apply it to all cases going forward
8. An MRO notices that a specific collection site has a 15% specimen rejection rate over three months. The BEST first step is to: → Conduct a site visit and review collector training records
9. A key QA indicator for split specimen testing performance is monitoring the rate of: → Split specimens confirmed at the retest laboratory vs. those that fail reconfirmation
10. Which standard of practice is MOST important for ensuring quality in Modifications & Change Orders? → Following evidence-based protocols while adapting to specific circumstances
11. Which document outlines ethical conduct for MROs? → MRO Code of Ethics
12. Which federal agency sets the guidelines for workplace drug testing? → SAMHSA
13. A laboratory's external proficiency testing (PT) result is reported as 'fail' for one analyte. Under HHS Mandatory Guidelines, the laboratory must: → Investigate and submit a corrective action plan to HHS within 30 days
14. Which of the following is an ethically appropriate reason for an MRO to recuse himself from reviewing a specific donor's specimen? → The donor is the MRO's immediate family member
15. Which of the following is a key compliance requirement for laboratories? → Be federally certified and quality-controlled
16. Which standard of practice is MOST important for ensuring quality in Performance Monitoring & QA? → Following evidence-based protocols while adapting to specific circumstances
17. Which federal regulation outlines the procedures for drug testing in the workplace? → 49 CFR Part 40
18. Which document provides the primary federal quality standards that HHS-certified laboratories must follow for workplace drug testing? → HHS Mandatory Guidelines for Federal Workplace Drug Testing Programs
19. Which specimen type is most commonly used in federally regulated drug testing? → Urine
20. In Small Business Programs, what is the FIRST step a MRO professional should take when encountering a new case or situation? → Conduct a comprehensive assessment and gather all relevant information
21. Which standard of practice is MOST important for ensuring quality in Small Business Programs? → Following evidence-based protocols while adapting to specific circumstances
22. What is the chain of custody in drug testing? → Documentation tracking specimen handling
23. What is the PRIMARY purpose of continuing education requirements in Modifications & Change Orders for MRO professionals? → Maintaining current knowledge and competency as the field evolves
24. What is the PRIMARY purpose of continuing education requirements in Cost & Pricing Analysis for MRO professionals? → Maintaining current knowledge and competency as the field evolves
25. What is the role of the MRO when reviewing a confirmed positive test result? → Determine if a valid medical reason exists
26. In Performance Monitoring & QA, what is the FIRST step a MRO professional should take when encountering a new case or situation? → Conduct a comprehensive assessment and gather all relevant information
27. Which standard of practice is MOST important for ensuring quality in Federal Acquisition Regulations? → Following evidence-based protocols while adapting to specific circumstances
28. In Source Selection & Evaluation, what is the FIRST step a MRO professional should take when encountering a new case or situation? → Conduct a comprehensive assessment and gather all relevant information
29. What is the primary purpose of the MRO's interview with a donor following a non-negative drug test result? → To determine whether a legitimate medical explanation accounts for the result
30. In Contract Closeout Procedures, what is the FIRST step a MRO professional should take when encountering a new case or situation? → Conduct a comprehensive assessment and gather all relevant information