Medical Laboratory Technician Hematology and Coagulation Questions and Answers

Question 1

A patient is receiving unfractionated heparin therapy for deep vein thrombosis.
The clinical protocol requires maintaining the aPTT at 1.5 to 2.5 times the mean of the normal range.
The laboratory's normal aPTT range is 28-38 seconds.
Which of the following results is within the therapeutic range for this patient?

Accepted Answer

80 seconds

Answer

40 seconds

Answer

100 seconds

Answer

25 seconds

Question 2

A peripheral blood smear shows red blood cells arranged in stacks, resembling coins. This finding is best described as:

Accepted Answer

Rouleaux

Answer

Agglutination

Answer

Spherocytosis

Answer

Anisocytosis

Question 3

Which of the following laboratory tests is most crucial for monitoring the effectiveness of warfarin (Coumadin®) therapy?

Accepted Answer

Prothrombin Time / International Normalized Ratio (PT/INR)

Answer

Activated Partial Thromboplastin Time (aPTT)

Answer

Fibrinogen Level

Answer

Thrombin Time (TT)

Question 4

Given the following patient data, calculate the Mean Corpuscular Hemoglobin (MCH):
Hemoglobin: 15 g/dL
RBC Count: 5.0 x 10^12/L
Hematocrit: 45%

Accepted Answer

30 pg

Answer

33.3 g/dL

Answer

90 fL

Answer

10 g/dL

Question 5

A patient presents with mucocutaneous bleeding. Laboratory findings include a normal platelet count, giant platelets on the peripheral smear, and impaired platelet aggregation with ristocetin. Aggregation with ADP, collagen, and epinephrine is normal. These findings are most consistent with which platelet disorder?

Accepted Answer

Bernard-Soulier Syndrome

Answer

Glanzmann Thrombasthenia

Answer

von Willebrand Disease

Answer

Idiopathic Thrombocytopenic Purpura (ITP)

Question 6

An elevated D-dimer test is most clinically significant for which of the following applications?

Accepted Answer

Ruling out venous thromboembolism (VTE) in a low-probability patient

Answer

Confirming a diagnosis of Deep Vein Thrombosis (DVT)

Answer

Monitoring heparin therapy effectiveness

Answer

Diagnosing Hemophilia A