Medical Laboratory Technician Hematology and Coagulation Questions and Answers Flashcards
6 cards from real Medical Laboratory Technician Exam practice questions. Tap to flip, then mark Knew It or Still Learning — missed cards come back until you master them.
Read the first 6 Medical Laboratory Technician Hematology and Coagulation Questions and Answers flashcards as text
Which red blood cell inclusion is identified using a supravital stain such as new methylene blue?
Answer: Heinz bodies
Heinz bodies are denatured hemoglobin inclusions that require supravital staining with new methylene blue or crystal violet for visualization.
In von Willebrand disease type 1, which laboratory finding is most expected?
Answer: Prolonged bleeding time with decreased vWF antigen
Type 1 von Willebrand disease is a partial quantitative deficiency of vWF, leading to prolonged bleeding time and decreased vWF antigen levels.
A peripheral blood smear reveals teardrop cells (dacrocytes), nucleated red blood cells, and immature granulocytes. This leukoerythroblastic picture is most suggestive of which condition?
Answer: Myelofibrosis
A leukoerythroblastic blood picture with dacrocytes is the classic peripheral smear finding in myelofibrosis due to marrow replacement by fibrosis.
What is the principle behind the prothrombin time (PT) test?
Answer: Tissue factor activates the extrinsic pathway in recalcified plasma
The PT test measures the extrinsic and common pathways by adding tissue thromboplastin (tissue factor) and calcium to citrated plasma and timing clot formation.
Which cell line is most characteristically elevated in chronic myelogenous leukemia (CML) during the chronic phase?
Answer: Granulocytic series with basophilia
CML in chronic phase shows marked granulocytic proliferation with a left shift and characteristic absolute basophilia in the peripheral blood.
A patient on warfarin therapy has an INR of 5.2 with active bleeding. What is the most appropriate immediate laboratory-relevant intervention?
Answer: Administer vitamin K and fresh frozen plasma
An elevated INR with active bleeding in a warfarin patient requires immediate reversal with vitamin K and fresh frozen plasma to replace depleted coagulation factors.