FREE Medical Laboratory Technician Blood Banking and Transfusion Questions and Answers Flashcards
6 cards from real Medical Laboratory Technician Exam practice questions. Tap to flip, then mark Knew It or Still Learning — missed cards come back until you master them.
Read the first 6 FREE Medical Laboratory Technician Blood Banking and Transfusion Questions and Answers flashcards as text
A patient with blood type AB positive requires a platelet transfusion, but only type O platelets are available. What is the primary concern with this transfusion?
Answer: Anti-A and anti-B antibodies in the donor plasma may cause hemolysis
Type O platelet units contain donor plasma with anti-A and anti-B antibodies that can cause hemolysis of the recipient's red blood cells.
During an antibody identification panel, a technologist notices that all panel cells positive for the Jka antigen are reactive. The autocontrol is negative. Which additional test would best confirm anti-Jka?
Answer: Enzyme-treated panel cells
Kidd antibodies are enhanced by enzyme treatment, so enzyme-treated panel cells would strengthen the reactions and help confirm anti-Jka.
A crossmatch is incompatible at the antihuman globulin (AHG) phase. The antibody screen is negative. What is the most likely cause?
Answer: An antibody directed against a low-frequency antigen on the donor cells
A negative antibody screen with an incompatible crossmatch at AHG suggests an antibody to a low-frequency antigen present on the donor cells but absent from screening cells.
Which of the following is the most appropriate product for a neonate requiring an exchange transfusion for hemolytic disease of the fetus and newborn (HDFN) caused by anti-D?
Answer: Group O, Rh-negative red blood cells resuspended in AB plasma
Group O Rh-negative RBCs avoid ABO and Rh incompatibility, and AB plasma lacks anti-A and anti-B antibodies that could harm the neonate's cells.
A blood bank technologist performs a DAT on a post-transfusion sample and obtains a mixed-field reaction. What does this finding most likely indicate?
Answer: Circulating transfused donor cells are being coated with recipient antibody in vivo
A mixed-field DAT after transfusion indicates that some cells (transfused donor cells) are coated with antibody while the patient's own cells remain uncoated.
Which storage lesion change is most significant in red blood cells stored beyond 35 days in CPDA-1?
Answer: Decreased 2,3-DPG levels causing increased oxygen affinity
Stored red blood cells progressively lose 2,3-DPG, which increases hemoglobin's oxygen affinity and reduces oxygen delivery to tissues.