Blood Bank and Transfusion Flashcards
7 cards from real Medical Laboratory Technician Exam practice questions. Tap to flip, then mark Knew It or Still Learning — missed cards come back until you master them.
Read the first 7 Blood Bank and Transfusion flashcards as text
Granulocyte transfusions should be irradiated primarily to prevent:
Answer: Transfusion-associated graft-versus-host disease
Granulocyte components contain large numbers of T lymphocytes, making irradiation essential to prevent TA-GvHD.
A patient types as group O with anti-A and anti-B but shows a weak forward reaction with anti-A,B reagent. The most likely explanation is:
Answer: A subgroup such as Ax
Weak A subgroups (Ax, Aend) may not react with individual anti-A but can react with the cross-reacting anti-A,B reagent, revealing residual A antigen.
When a transfusion reaction is suspected, which is the FIRST action the technologist should take?
Answer: Stop the transfusion and notify the physician
Stopping the transfusion immediately limits antigen-antibody exposure; clinical management by the physician follows simultaneously.
Which coagulation factor is the ONLY one NOT found in cryoprecipitate?
Answer: Factor V
Cryoprecipitate is enriched in Factors VIII, XIII, fibrinogen, fibronectin, and vWF but does not contain Factor V in significant amounts.
A patient has a positive DAT and a panreactive antibody panel. The most appropriate next step is to:
Answer: Perform an autoadsorption to remove autoantibody before alloantibody identification
Autoadsorption removes warm autoantibody from the serum, allowing underlying alloantibodies to be detected before a potentially life-saving transfusion.
The McLeod phenotype is associated with which clinical syndrome?
Answer: Chronic granulomatous disease
The McLeod phenotype results from absence of the XK protein and is associated with X-linked chronic granulomatous disease and acanthocytic hemolytic anemia.
Platelet refractoriness is best evaluated by calculating the:
Answer: Corrected count increment (CCI) at 10–60 minutes post-transfusion
A CCI below 5,000 at 10–60 minutes post-transfusion on two occasions indicates immune-mediated refractoriness; a low CCI at 24 hours suggests non-immune causes.