Medical Laboratory Technician Exam FREE Medical Laboratory Technician Blood Banking and Transfusion Questions and Answers 3

Question 1

A patient develops fever, flank pain, and hemoglobinuria 30 minutes after starting a red blood cell transfusion. Which type of transfusion reaction is most likely?

Accepted Answer

Acute hemolytic transfusion reaction

Answer

Febrile non-hemolytic transfusion reaction

Answer

Transfusion-related acute lung injury

Answer

Bacterial contamination of the unit

Question 2

When performing elution on antibody-coated red blood cells, which method is most effective for recovering warm-reactive IgG antibodies?

Accepted Answer

Acid elution

Answer

Cold elution

Answer

Chloroform elution

Answer

Heat elution at 56°C for 30 minutes

Question 3

A patient with sickle cell disease has developed multiple alloantibodies after chronic transfusions. Which antigen matching strategy best prevents further alloimmunization?

Accepted Answer

Extended phenotype matching for Rh and Kell antigens at minimum

Answer

ABO and Rh(D) matching only

Answer

Crossmatch-compatible units without additional phenotyping

Answer

Irradiated, leukoreduced random donor units

Question 4

Irradiation of blood components is performed to prevent which transfusion complication?

Accepted Answer

Transfusion-associated graft-versus-host disease

Answer

Transfusion-related acute lung injury

Answer

Febrile non-hemolytic transfusion reactions

Answer

Post-transfusion purpura

Question 5

Which antibody is characteristically associated with a delayed hemolytic transfusion reaction occurring 7-10 days post-transfusion?

Accepted Answer

Anti-Jka

Answer

Anti-A

Answer

Anti-M

Answer

Anti-Lewis a

Question 6

What is the primary purpose of performing a type and screen rather than a full crossmatch for surgical patients?

Accepted Answer

To detect clinically significant unexpected antibodies while reducing unnecessary crossmatching

Answer

To eliminate the need for ABO and Rh typing

Answer

To replace the need for an antibody identification panel

Answer

To ensure immediate-spin compatibility with all donor units