Medical Knowledge Pathophysiology 1 — Questions and Answers
Question 1: What is the classic symptom triad of Type 1 Diabetes Mellitus?
- Fatigue, fever, and weight gain
- Polyuria, polydipsia, and polyphagia (Correct answer)
- Chest pain, dyspnea, and diaphoresis
- Nausea, vomiting, and diarrhea
Correct answer: Polyuria, polydipsia, and polyphagia
The classic triad of Type 1 DM consists of frequent urination, excessive thirst, and increased hunger due to absolute insulin deficiency.
Question 2: Which condition involves cholesterol-rich plaque buildup in arterial walls?
- Pulmonary embolism
- Atherosclerosis (Correct answer)
- Myocarditis
- Pericarditis
Correct answer: Atherosclerosis
Atherosclerosis involves accumulation of lipid-laden plaques in arterial walls, narrowing the lumen and reducing blood flow.
Question 3: What is the primary pathophysiological mechanism in asthma?
- Alveolar destruction
- Airway inflammation and bronchoconstriction (Correct answer)
- Pleural fluid accumulation
- Pulmonary hypertension
Correct answer: Airway inflammation and bronchoconstriction
Asthma involves chronic airway inflammation, bronchoconstriction, and mucus hypersecretion causing reversible airflow obstruction.
Question 4: What happens during myocardial infarction?
- Heart inflammation from infection
- Irreversible cardiac muscle death from prolonged ischemia (Correct answer)
- Fluid accumulation around the heart
- Heart valve prolapse
Correct answer: Irreversible cardiac muscle death from prolonged ischemia
Myocardial infarction occurs when prolonged coronary artery occlusion causes irreversible necrosis of cardiac muscle tissue.
Question 5: Which disease results from autoimmune destruction of pancreatic beta cells?
- Type 2 Diabetes
- Cushing's Syndrome
- Type 1 Diabetes (Correct answer)
- Graves' Disease
Correct answer: Type 1 Diabetes
Type 1 DM results from autoimmune destruction of insulin-producing beta cells, leading to absolute insulin deficiency.
Question 6: What is septic shock?
- Shock from major blood loss
- Life-threatening hypoperfusion from dysregulated infection response (Correct answer)
- Shock from severe allergic reaction
- Shock from pump failure
Correct answer: Life-threatening hypoperfusion from dysregulated infection response
Septic shock is a life-threatening state caused by dysregulated host response to infection, featuring refractory hypotension and organ dysfunction.
What is the classic symptom triad of Type 1 Diabetes Mellitus?