MBBS Biochemistry 2

Question 1

Gaucher disease results from deficiency of which enzyme?

Accepted Answer

Glucocerebrosidase (beta-glucosidase)

Answer

Sphingomyelinase

Answer

Hexosaminidase A

Answer

Alpha-galactosidase A

Question 2

Which of the following is the primary product of the pentose phosphate pathway?

Accepted Answer

NADPH and ribose-5-phosphate

Answer

ATP and pyruvate

Answer

Acetyl-CoA and NADH

Answer

Oxaloacetate and FADH2

Question 3

The DNA double helix is held together by which type of bonds between base pairs?

Accepted Answer

Hydrogen bonds

Answer

Covalent bonds

Answer

Ionic bonds

Answer

Disulfide bonds

Question 4

Which lipoprotein is responsible for transporting cholesterol from peripheral tissues to the liver (reverse cholesterol transport)?

Accepted Answer

HDL

Answer

Chylomicrons

Answer

VLDL

Answer

LDL

Question 5

Vitamin B12 deficiency causes megaloblastic anemia through impaired synthesis of which molecule?

Accepted Answer

Thymidine (dTMP)

Answer

Heme

Answer

Globin chains

Answer

Ferritin

Question 6

Which enzyme converts fibrinogen to fibrin in the coagulation cascade?

Accepted Answer

Thrombin

Answer

Factor X

Answer

Prothrombin

Answer

Plasmin