MACE Drug Identification 5 — Questions and Answers
Question 1: Which medication is a nucleoside reverse transcriptase inhibitor (NRTI) used in HIV treatment?
- Tenofovir (Correct answer)
- Ritonavir
- Efavirenz
- Raltegravir
Correct answer: Tenofovir
Tenofovir is an NRTI that inhibits reverse transcriptase by competing with the natural substrate, blocking HIV replication.
Question 2: Which drug is a first-generation cephalosporin antibiotic commonly used for skin infections?
- Cephalexin (Correct answer)
- Ceftriaxone
- Cefepime
- Ceftazidime
Correct answer: Cephalexin
Cephalexin is a first-generation cephalosporin with excellent gram-positive coverage, commonly used for skin and soft tissue infections.
Question 3: A medication tech identifies a drug ending in '-triptan.' What condition is it used to treat?
- Epilepsy
- Migraine headaches (Correct answer)
- Parkinson's disease
- Depression
Correct answer: Migraine headaches
Drugs ending in '-triptan' are serotonin receptor agonists (triptans) used specifically for acute migraine treatment.
Question 4: Which of the following is an inhaled corticosteroid (ICS) used for long-term asthma control?
- Albuterol
- Ipratropium
- Fluticasone (Correct answer)
- Montelukast
Correct answer: Fluticasone
Fluticasone is an inhaled corticosteroid that reduces airway inflammation for maintenance asthma therapy.
Question 5: Which antiepileptic drug is also used for bipolar disorder and is known to require serum level monitoring?
- Gabapentin
- Valproic acid (Correct answer)
- Topiramate
- Levetiracetam
Correct answer: Valproic acid
Valproic acid has a narrow therapeutic index and is used for epilepsy and bipolar disorder, requiring regular serum level monitoring.
Question 6: Sildenafil (Viagra) is a phosphodiesterase-5 (PDE-5) inhibitor. Which drug interaction is most dangerous with sildenafil?
- Statins
- Nitrates (Correct answer)
- Beta blockers
- ACE inhibitors
Correct answer: Nitrates
Combining sildenafil with nitrates causes severe hypotension because both drugs lower blood pressure through different vasodilatory mechanisms.
Question 7: Which medication is a biphosphonate used to treat osteoporosis by inhibiting bone resorption?
- Calcitonin
- Alendronate (Correct answer)
- Raloxifene
- Teriparatide
Correct answer: Alendronate
Alendronate is a bisphosphonate that inhibits osteoclast activity, slowing bone resorption and reducing fracture risk in osteoporosis.
MACE Drug Identification 5
Which medication is a nucleoside reverse transcriptase inhibitor (NRTI) used in HIV treatment?