A 58-year-old male with acute myeloid leukemia is undergoing induction chemotherapy.
He develops a fever of 39.2°C (102.6°F) and his absolute neutrophil count is 150 cells/mm³.
He is hemodynamically stable with no clear source of infection on initial examination.
According to IDSA guidelines, which of the following is the most appropriate initial empiric antibiotic regimen?