Pharmacology and Pain Management Flashcards
6 cards from real INBDE practice questions. Tap to flip, then mark Knew It or Still Learning — missed cards come back until you master them.
Read the first 6 Pharmacology and Pain Management flashcards as text
Which local anesthetic has the longest duration of action?
Answer: Bupivacaine
Bupivacaine (Marcaine) has the longest duration of pulpal and soft tissue anesthesia among common dental local anesthetics due to its high protein-binding affinity.
Epinephrine is added to local anesthetic solutions primarily to:
Answer: Prolong the duration of anesthesia by causing vasoconstriction
Epinephrine causes local vasoconstriction, reducing the rate of systemic absorption of the local anesthetic and thereby prolonging its duration and reducing toxicity.
A patient taking warfarin requires a dental extraction. The INR is 2.5. The most appropriate management is to:
Answer: Proceed with extraction using local hemostatic measures
For patients on warfarin with an INR ≤3.5, routine dental extractions can proceed safely with local hemostatic measures such as pressure and sutures.
Which analgesic is contraindicated in patients with aspirin-exacerbated respiratory disease (AERD)?
Answer: Ibuprofen
NSAIDs like ibuprofen inhibit COX-1, shunting arachidonic acid toward leukotriene production, which triggers bronchoconstriction in patients with AERD.
Tetracyclines are contraindicated in children under 8 years of age because they:
Answer: Cause permanent tooth discoloration and enamel hypoplasia
Tetracyclines chelate calcium and incorporate into developing teeth and bone, causing permanent yellow-gray discoloration and enamel hypoplasia in children under 8.
Which benzodiazepine is most commonly used for IV conscious sedation in dentistry?
Answer: Midazolam
Midazolam is preferred for IV conscious sedation in dentistry due to its rapid onset, short duration, water solubility, and superior amnestic properties.