Practice Test GeeksIBD - Inflammatory Bowel Disease Practice Test
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Knowledge Flashcards

7 cards from real IBD practice questions. Tap to flip, then mark Knew It or Still Learning — missed cards come back until you master them.

Read the first 7 Knowledge flashcards as text

  1. Which serological marker is most strongly associated with Crohn's disease?

    Answer: ASCA (anti-Saccharomyces cerevisiae antibody)

    ASCA is found in approximately 60-70% of Crohn's disease patients and is a useful distinguishing marker from UC.

  2. What is the primary mechanism of action of vedolizumab in IBD treatment?

    Answer: Gut-selective integrin blockade (anti-α4β7)

    Vedolizumab selectively blocks α4β7 integrin, preventing lymphocyte trafficking specifically to the gut.

  3. Which complication of Crohn's disease is characterized by an abnormal connection between two loops of bowel?

    Answer: Entero-enteric fistula

    An entero-enteric fistula is an abnormal passage connecting two segments of intestine, a transmural complication characteristic of Crohn's disease.

  4. What is the Montreal Classification used to describe in IBD?

    Answer: Extent and behavior of Crohn's disease and extent of UC

    The Montreal Classification categorizes Crohn's disease by age of onset, location, and behavior, and categorizes UC by extent of involvement.

  5. Toxic megacolon is most commonly associated with which condition?

    Answer: Severe ulcerative colitis

    Toxic megacolon, defined as colonic dilation >6 cm with systemic toxicity, is a life-threatening complication most often seen in severe ulcerative colitis.

  6. Which amino salicylate formulation is specifically designed for proximal small bowel Crohn's disease delivery?

    Answer: Pentasa

    Pentasa (mesalamine) uses ethylcellulose microgranules that release drug throughout the GI tract from the duodenum onward, making it suitable for small bowel disease.

  7. What does the term 'skip lesions' describe in the context of IBD?

    Answer: Patchy areas of inflammation separated by normal mucosa in Crohn's disease

    Skip lesions refer to discontinuous segments of inflamed bowel interspersed with normal-appearing mucosa, a hallmark endoscopic feature of Crohn's disease.