Cost-Effectiveness Analysis Flashcards
7 cards from real HAC practice questions. Tap to flip, then mark Knew It or Still Learning — missed cards come back until you master them.
Read the first 7 Cost-Effectiveness Analysis flashcards as text
Net Monetary Benefit (NMB) is calculated as:
Answer: (Willingness-to-pay threshold × incremental QALYs) − incremental costs
NMB converts health outcomes to monetary units using the WTP threshold and subtracts incremental costs; positive NMB indicates cost-effectiveness.
A 'dominated' intervention in CEA is one that is:
Answer: More costly and less effective than the comparator
A dominated intervention costs more and produces worse health outcomes than its comparator, making it irrational to choose.
Extended dominance occurs when an intervention is ruled out because:
Answer: A combination of two other interventions produces better outcomes at lower cost
Extended dominance eliminates an option whose ICER is higher than that of a more effective alternative, making a linear combination preferable.
In healthcare CEA, the standard discount rate recommended by the US Panel on Cost-Effectiveness is:
Answer: 3% for both costs and health outcomes
The 2nd US Panel on Cost-Effectiveness in Health and Medicine recommends a 3% annual discount rate for both costs and health outcomes.
What is the primary advantage of using QALYs over life-years gained as an outcome measure in CEA?
Answer: QALYs incorporate both length and quality of life, enabling cross-disease comparisons
QALYs combine survival duration with health-related quality of life, allowing comparison of interventions across different disease areas.
Which instrument is commonly used to derive EQ-5D utility values for QALY calculation?
Answer: EQ-5D questionnaire with population-based value set
The EQ-5D is a standardized instrument whose dimension scores are mapped to utility values using population preference-based value sets.
Time trade-off (TTO) is a method used to:
Answer: Elicit health state utility values by asking individuals how much life they would trade for perfect health
TTO elicits utility values by asking respondents to choose between living in a health state for a defined period versus fewer years in perfect health.